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01 — About the Firm

Who We Are

A boutique executive search and advisory firm built for the biopharmaceutical sector — serving the full spectrum from emerging biotechs to established large pharma.

The Firm

Built for Biopharma

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Blake & Michaels is a boutique executive search and advisory firm serving the full spectrum of the biopharmaceutical sector — from emerging venture-backed biotechs and mid-sized development-stage companies to established large pharma organizations navigating leadership transitions.

We specialize in placing C-suite executives and functional heads at companies navigating critical inflection points: pre-IND, crossover rounds, Phase II readouts, pre-IPO structuring, and public company transitions. Our mandates span organizations of every scale — from first executive hires at Series A companies to C-suite upgrades at publicly traded large pharma.

Operating as a high-touch alternative to global firms, we deliver sector depth, board fluency, and disciplined execution without institutional bureaucracy. Search, to us, is not transactional — it is strategic risk management.

Blake & Michaels maintains active relationships across clinical KOLs and physician-scientists, venture syndicate members, and board directors in oncology, rare and orphan disease, and advanced modalities — giving us the proximity to surface candidates who are rarely visible through conventional search channels.

Whether our client is a Series A biotech structuring its first clinical team, a mid-sized company preparing for a crossover round, or a large pharma organization replacing a departing CMO, we bring the same discipline: calibrated success profiles, capital-aware strategy, and high-signal candidate evaluation.

Venture-Backed Biotech
Series A through pre-IPO — first executive hires to crossover structuring.
Mid-Sized Biopharma
Development-stage and commercial-stage companies scaling clinical and functional leadership.
Large Pharma
Established organizations requiring discrete, high-urgency C-suite and functional head placement.
Leadership

Founder & Principal

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Jason
Stewart
Founder & Managing Principal
Blake & Michaels LLC
LinkedIn Profile

Founded and led by Jason Stewart, Blake & Michaels brings deep sector expertise, active network relationships, and a disciplined approach to every engagement — without the institutional overhead or competing priorities of global search firms.

Jason maintains active relationships across clinical KOLs and physician-scientists, venture syndicate members, and board directors in oncology, rare and orphan disease, and advanced modalities. This proximity surfaces candidates who are rarely visible through conventional search channels — individuals whose expertise, timing, and trajectory align with the precise moment a company faces.

With experience spanning Series A biotechs to top-10 global pharma, Jason brings the same rigor to a first executive hire as to a C-suite upgrade at a publicly traded company: calibrated success profiles, capital-aware strategy, and high-signal candidate evaluation from a position of genuine sector fluency.

Coverage

Therapeutic Areas & Modalities

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Therapeutic Areas
Oncology
Solid tumors, hematologic malignancies, immuno-oncology, ADCs, and precision medicine platforms across early and late-stage development.
Rare & Orphan Disease
Gene therapy, enzyme replacement, RNA-targeted therapies, and small molecule approaches in rare metabolic, neurological, and genetic conditions.
Neuroscience
CNS disorders, neurodegeneration, psychiatric conditions, and neurological rare diseases spanning small molecules and biologics.
Immunology & Inflammation
Autoimmune, inflammatory, and fibrotic disease across biologics, small molecules, and next-generation targeted therapies.
Cardiovascular & Metabolic
Cardiometabolic disease, heart failure, and lipid disorders — including CRISPR and RNA-based modalities entering the space.
Infectious Disease & Vaccines
Antiviral, antibacterial, and vaccine development across mRNA platforms, biologics, and small molecule antivirals.
Modalities Small Molecule Cell & Gene Therapy mRNA & RNA-Targeted Biologics & Antibodies ADC CRISPR & Gene Editing Radiopharmaceuticals Enzyme Replacement Combination Products Oligonucleotides

Ready to Engage?

All initial conversations are confidential. If you are approaching an inflection point and believe leadership quality will determine your trajectory — we are ready to engage.

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